EmbryoScope® time-lapse system

EmbryoScope® time-lapse system is a unique platform facilitating improved IVF treatment, flexible work routines and effective communication, through comprehensive documentation of embryo development and evolving improvements in selection.

EmbryoScope® time-lapse system allows the uninterrupted culture of embryos whilst maximizing the amount of embryo development information collected. Evolving selection criteria are helping clinics worldwide to improve their IVF practise. Our solution constitutes a platform which is the basis for Improved IVF treatment and clinic digitization.

EmbryoScope® time-lapse incubator offers you:

Undisturbed stable incubation

  • Tri-gas incubator allows fast and accurate regulation of CO2 and O2 concentrations with minimal gas consumption
  • Unique temperature control by direct heat transfer to individual media-filled wells. Temperature is virtually unchanged by opening chamber (<0.2° C) when adding or removing patient samples
  • Recovery of CO2 concentration in less than 5 minutes and O2 in less than 15 minutes after closing chamber
  • Continuous circulation and purification of air supply with residence time of less than 20 minutes
  • Air purified by active carbon and HEPA filter. Removes VOCs and retains 99.97 % of particles larger than 0.3 μm
  • Simplifies compliance with EU Directive 2004/23/EC by automatic logging of running conditions such as temperature, CO2 and O2 concentration to patient data files
  • Dry incubation without water pans eliminates problems with water condensation and fungal growth on surfaces in high humidity

Time-lapse monitoring

  • Fully automated detection and focusing of up to 72 embryos (6 patient culture dishes with 12 embryos in each dish)
  • Image acquisition in multiple focal planes of all embryos
  • High-quality Hoffman modulation contrast optics allows observation of key morphological features
  • Special Leica optics designed for red light at 635 nm to eliminate high energy light exposure

Add-on features

  • Print labels for the EmbryoSlide® culture dish and scan them automatically in the EmbryoScope® time-lapse incubator
  • Inform patients about their IVF treatment and development of their embryos with the FertiliTech Counseling App
  • Annotate embryos from multiple EmbryoViewer® workstations (requires ES Zoi server)

Download our Product Information brochure or find the technical specifications of the system below.

EmbryoScope® time-lapse system technical specifications

EmbryoScope® time-lapse incubator

Instrument

Capacity:                     
Six disposable EmbryoSlide® culture dishes holding 12 embryos each
Operation:                   
Individual culture dishes may be inserted and removed independently
Dimensions:                 
W x D x H (60.3 x 56.0 x 43.5) cm / (23.7 x 22 x 17.2) in
Weight:                       
60 kg / 121 lbs
Input voltage:
110-240 V AC
Power consumption:
120 W
Operating range:
20 °C – 30 °C
Alarm system:
Continuous internal system integrity check for separate subsystems of the instrument. Monitoring of incubation conditions and subsystem integrity; audible and visible alerts when incubation conditions out of range.
 

Image acquisition

Focal planes: 
Select up to 17 focal points at each time point in user defined vertical increments
Allowed number of focal planes depend on selected cycle time
Built-in microscope:
Leica 20x, 0.40 LWD Hoffman modulation contrast objective specialized for 635 nm illumination
Camera resolution:
1280 × 1024 pixels, 3 pixels per μm, monochrome, 8-bit
Embryo illumination:
≤ 0.032s per image using single red LED (635nm) gives 34μW cm-2 for image acquisition
Time between acquisitions:
10 min. cycle time for 7 focal planes, 2 min cycle time with single focal plane
 

Tri-gas incubator Integrated in instrument

Temperature: 
30 °C to 45 °C ± 0.2 °C*
* Temperature range:
Temperature set-point must be at least 7 °C above ambient temperature and ambient temperature must be less than 30 °C
Oxygen:
5 % to 20 % ± 0.3 %
CO2:
2 % to 10 % ± 0.2 %
Active air circulation:
Full purification of gas volume every 20 minutes
Volatile organic compounds:
Removed by active carbon filter
Particles:
Removed by HEPA filter which retains 99.97 % particles >0.3 μm
 

Data acquisition Intel based fanless embedded PC

Network:
100 Mb Ethernet
Operating system:
Microsoft Windows®
Data exchange:
Ethernet
Data format for images:
JPEG
Monitor:
12.1” embedded touch screen

Europe: CE-marked class IIa medical device
USA-FDA 510(k) clearance

ES Zoi™ server

Dimensions:
W x D x H (3.5 x 18.0 x 18.0) cm / (1.4 x 7.1 x 7.1) in
Weight:
1.3 kg / 2.8 lbs
Input voltage:
110-240 V AC
Capacity:
Typically 2500 treaments (upgradable)
Depends on image aquisition settings

Europe: CE-marked class I medical device